Other Phosphoramidites
DMTr-2'-O-Trifluoroacetamindo propyl-rC(Bz)-3'-CE-Phosphoramidite
Quick view. We supply DMTr-2'-O-Trifluoroacetamindo propyl-rC(Bz)-3'-CE-Phosphoramidite as a hydrophobic or alkyl-modified phosphoramidite for installing lipophilic side chains into oligonucleotides. CAS 165381-54-4. Catalog target purity: Specification on request.
Product profile
DMTr-2'-O-Trifluoroacetamindo propyl-rC(Bz)-3'-CE-Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C51H58F3N6O10P; molecular weight 1003.01).
DMTr-2'-O-Trifluoroacetamindo propyl-rC(Bz)-3'-CE-Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For DMTr-2'-O-Trifluoroacetamindo propyl-rC(Bz)-3'-CE-Phosphoramidite, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- N4-Benzoyl-5'-O-DMTr-2'-O-(N3-trifluoroacetyl)aminopropylcytidine3'-CEDphosphoramidite
- DMT-2'-O-Trifluoroacetamindo propyl-rC(Bz)-3'-CE-Phosphoramidite
- DMTr-2'-O-Trifluoroacetamindo propyl-rC(Bz)-3'-2-cyanoethyl phosphoramidite
Useful catalog search terms
- CAS 165381-54-4
- Protected oligonucleotide phosphoramidite building block
- DMTr/DMT protection
- phosphoramidite coupling group
- Other Phosphoramidites
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; phosphoramidite coupling group |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- N4-Benzoyl-5’-O-DMTr-2’-O-(N3-trifluoroacetyl) aminopropyl cytidine 3’-CED phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe DMTr-2'-O-Trifluoroacetamindo propyl-rC(Bz)-3'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for DMTr-2'-O-Trifluoroacetamindo propyl-rC(Bz)-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-OP-0049 and CAS 165381-54-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Other Phosphoramidites product family and its named chemistry.