Other Phosphoramidites
DMTr-2'-O-Trifluoroacetamido propyl-rC(Bz)-3'-CE-Phosphoramidite
Quick view. A protected cytidine 3'-CE phosphoramidite bearing a 2'-O-[3-(N-trifluoroacetamido)propyl] substituent, 5'-O-DMTr protection, and N4-benzoyl base protection. CAS 165381-54-4. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
DMTr-2'-O-Trifluoroacetamido propyl-rC(Bz)-3'-CE-Phosphoramidite is classified as protected cytidine phosphoramidite (Formula C51H58F3N6O10P; molecular weight 1003.03).
DMTr-2'-O-Trifluoroacetamido propyl-rC(Bz)-3'-CE-Phosphoramidite is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For DMTr-2'-O-Trifluoroacetamido propyl-rC(Bz)-3'-CE-Phosphoramidite, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- N4-Benzoyl-5'-O-DMTr-2'-O-(N3-trifluoroacetyl) aminopropyl cytidine 3'-CED phosphoramidite
Useful catalog search terms
- 165381-54-4
- 2'-O-aminopropyl cytidine phosphoramidite
Physicochemical data
| Ribose modification | 2'-O-[3-(N-trifluoroacetamido)propyl] |
|---|---|
| Protecting groups | 5'-O-DMTr; N4-benzoyl; N-trifluoroacetyl |
| Phosphoramidite group | 3'-O-(2-cyanoethyl N,N-diisopropylphosphoramidite) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe DMTr-2'-O-Trifluoroacetamido propyl-rC(Bz)-3'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-OP-00035'-O-DMTr-2'-O-MOE-rG(iBu) Bis(phosphoramidite)
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BX-OP-00045'-O-DMTr-2'-O-MOE-rT Bis(phosphoramidite)
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BX-OP-00065'-DMT Amino-Modifier C6 Phosphoramidite
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BX-OP-0007Bis(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-diisopropylphosphoramidite
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Frequently asked questions
Can the package size for DMTr-2'-O-Trifluoroacetamido propyl-rC(Bz)-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-OP-0049 and CAS 165381-54-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.