Thio Phosphoramidites
N6-Benzoyl-5'-O-DMTr-2'-deoxyadenosine-3'-PS phosphoramidite
Quick view. A protected 2'-deoxyadenosine building block bearing N6-benzoyl and 5'-O-DMTr groups with a 3'-S-(2-benzoylmercaptoethyl) pyrrolidino thiophosphoramidite functionality. CAS 178272-29-2. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
N6-Benzoyl-5'-O-DMTr-2'-deoxyadenosine-3'-PS phosphoramidite is classified as thio phosphoramidites (Formula C51H51N6O7PS2; molecular weight 955.10).
N6-Benzoyl-5'-O-DMTr-2'-deoxyadenosine-3'-PS phosphoramidite — Identity-defined dA(Bz)-3'-PS phosphoramidite for research workflows involving solid-phase oligonucleotide synthesis.
For N6-Benzoyl-5'-O-DMTr-2'-deoxyadenosine-3'-PS phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- dA(Bz)-3'-PS phosphoramidite
- 5'-DMT-dA(Bz)-3'-PS phosphoramidite
- dA(Bz) thiophosphoramidite
Useful catalog search terms
- CAS 178272-29-2
Physicochemical data
| InChIKey | MLBWDUKKOAPDAN-OBBNISDBSA-N |
|---|---|
| Nucleoside | 2'-Deoxyadenosine |
| Base protection | N6-Benzoyl |
| 5' protection | DMTr |
| 3'-functionality | S-(2-benzoylmercaptoethyl) pyrrolidino thiophosphoramidite |
| InChI | InChI=1S/C51H51N6O7PS2/c1-60-41-24-20-39(21-25-41)51(38-18-10-5-11-19-38,40-22-26-42(61-2)27-23-40)62-33-44-43(64-65(56-28-12-13-29-56)67-31-30-66-50(59)37-16-8-4-9-17-37)32-45(63-44)57-35-54-46-47(52-34-53-48(46)57)55-49(58)36-14-6-3-7-15-36/h3-11,14-27,34-35,43-45H,12-13,28-33H2,1-2H3,(H,52,53,55,58)/t43-,44+,45+,65?/m0/s1 |
| SMILES | COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H](C[C@@H](O4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7)OP(N8CCCC8)SCCSC(=O)C9=CC=CC=C9 |
| Canonical SMILES | COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H](C[C@@H](O4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7)OP(N8CCCC8)SCCSC(=O)C9=CC=CC=C9 |
| PubChem CID | 10533897 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for N6-Benzoyl-5'-O-DMTr-2'-deoxyadenosine-3'-PS phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-TP-0006 and CAS 178272-29-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Thio Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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