Thio Phosphoramidites
N6-Benzoyl-5'-O-DMTr-2'-O-TBDMS-adenosine-3'-PS phosphoramidite
Quick view. A protected adenosine building block bearing N6-benzoyl, 5'-O-DMTr, and 2'-O-TBDMS groups with a 3'-S-(2-benzoylmercaptoethyl) pyrrolidino thiophosphoramidite functionality. CAS 1374755-65-3. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
N6-Benzoyl-5'-O-DMTr-2'-O-TBDMS-adenosine-3'-PS phosphoramidite is classified as thio phosphoramidites (Formula C57H65N6O8PS2Si; molecular weight 1085.36).
N6-Benzoyl-5'-O-DMTr-2'-O-TBDMS-adenosine-3'-PS phosphoramidite — Identity-defined 2'-O-TBDMS-rA(Bz)-3'-PS phosphoramidite for research workflows involving solid-phase oligonucleotide synthesis.
For N6-Benzoyl-5'-O-DMTr-2'-O-TBDMS-adenosine-3'-PS phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2'-O-TBDMS-rA(Bz)-3'-PS phosphoramidite
- 5'-DMT-2'-O-TBDMS-A(Bz)-3'-PS phosphoramidite
- 2'-OTBS A(Bz) thiophosphoramidite
Useful catalog search terms
- CAS 1374755-65-3
Physicochemical data
| InChIKey | ALJIYXCITZABFP-WOMFGPHHSA-N |
|---|---|
| Nucleoside | Adenosine |
| Base protection | N6-Benzoyl |
| 5' protection | DMTr |
| 2'-Protecting group | TBDMS |
| 3'-functionality | S-(2-benzoylmercaptoethyl) pyrrolidino thiophosphoramidite |
| PubChem CID | 102308172 |
| InChI | InChI=1S/C57H65N6O8PS2Si/c1-56(2,3)75(6,7)71-50-49(70-72(62-33-17-18-34-62)74-36-35-73-55(65)41-21-13-9-14-22-41)47(69-54(50)63-39-60-48-51(58-38-59-52(48)63)61-53(64)40-19-11-8-12-20-40)37-68-57(42-23-15-10-16-24-42,43-25-29-45(66-4)30-26-43)44-27-31-46(67-5)32-28-44/h8-16,19-32,38-39,47,49-50,54H,17-18,33-37H2,1-7H3,(H,58,59,61,64)/t47-,49-,50-,54-,72?/m1/s1 |
| SMILES | COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(NC(=O)c5ccccc5)ncnc43)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(SCCSC(=O)c2ccccc2)N2CCCC2)(c2ccccc2)c2ccc(OC)cc2)cc1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for N6-Benzoyl-5'-O-DMTr-2'-O-TBDMS-adenosine-3'-PS phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-TP-0005 and CAS 1374755-65-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Thio Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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