Thio Phosphoramidites
5'-DMT-2'-OMe-A(Bz)-3'-PS-Phosphoramidite
Quick view. 5'-DMT-2'-OMe-A(Bz)-3'-PS-Phosphoramidite is an N6-benzoyl-protected 2'-O-methyl adenosine thiophosphoramidite for research-use oligonucleotide synthesis. A public CAS number is not assigned for this exact form. Catalog target purity: HPLC ≥90%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5'-DMT-2'-OMe-A(Bz)-3'-PS-Phosphoramidite is classified as n6-benzoyl-protected 2'-o-methyl adenosine thiophosphoramidite (Formula C52H53N6O8PS2; molecular weight 985.12).
5'-DMT-2'-OMe-A(Bz)-3'-PS-Phosphoramidite — Protected 2'-O-methyl adenosine thiophosphoramidite building block for research-use solid-phase oligonucleotide synthesis.
For 5'-DMT-2'-OMe-A(Bz)-3'-PS-Phosphoramidite, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- 2'-OMe-rA(Bz)-3'-PS-Phosphoramidite
Useful catalog search terms
- HR-00216001
- C52H53N6O8PS2
- Thio Phosphoramidites
Physicochemical data
| Key structural motifs | N6-benzoyl adenine, 5'-DMT protection, 2'-O-methyl ribose, and a 3'-thiophosphoramidite bearing S-(2-benzoylthioethyl) and pyrrolidino substituents |
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Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 5'-DMT-2'-OMe-A(Bz)-3'-PS-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
5'-DMT-2'-F-dA(Bz)-3'-PS-Phosphoramidite
Thio Phosphoramidites · CAS: N/A
BX-TP-0004N6-Benzoyl-5'-O-DMTr-2'-O-MOE-adenosine-3'-PS phosphoramidite
Thio Phosphoramidites · CAS: 2360826-72-6
BX-TP-0005N6-Benzoyl-5'-O-DMTr-2'-O-TBDMS-adenosine-3'-PS phosphoramidite
Thio Phosphoramidites · CAS: 1374755-65-3
BX-TP-0006N6-Benzoyl-5'-O-DMTr-2'-deoxyadenosine-3'-PS phosphoramidite
Thio Phosphoramidites · CAS: 178272-29-2
BX-TP-00073'-Thio-dI CE-Phosphoramidite
Thio Phosphoramidites · CAS: 1334533-56-0
Frequently asked questions
Can the package size for 5'-DMT-2'-OMe-A(Bz)-3'-PS-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-TP-0002, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Thio Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.