Base-protected Nucleosides
2'-dA(Bz)
Quick view. We supply 2'-dA(Bz) as a base- or sugar-protected nucleoside intermediate for nucleoside, nucleotide and oligonucleotide building-block synthesis. CAS 4546-72-9. Catalog target purity: Specification on request.
Product profile
2'-dA(Bz) is classified as nucleoside or protected nucleoside intermediate (Formula C17H17N5O4; molecular weight 355.35).
2'-dA(Bz) can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-dA(Bz), reported solubility: DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:6): 0.14 mg/ml; DMSO: 15 mg/ml; Ethanol: 1 mg/ml. Storage: Store at 0°C.
Names and search terms
Confirmed or normalized name variants
- DA-BZ
- N6-BENZOYL-2'-DEOXYADENOSINE
- N6-BENZOYLDEOXYADENOSINE
- N6-BZ-2'-DEOXYADENOSINE
- n-benzoyl-2'-deoxy-adenosine
- N-BZ-DA
- n-benzoyl-2’-deoxy-adenosin
- BZ-DEOXYADENOSINE
Useful catalog search terms
- CAS 4546-72-9
- Nucleoside or protected nucleoside intermediate
- Base-protected Nucleosides
Physicochemical data
| Melting point | 120-122C |
|---|---|
| Density | 1.61±0.1 g/cm3(Predicted) |
| pKa | 7.87±0.43(Predicted) |
| Form | A crystalline solid |
| Color | White to off-white |
| InChI | InChI=1S/C17H17N5O4/c23-7-12-11(24)6-13(26-12)22-9-20-14-15(18-8-19-16(14)22)21-17(25)10-4-2-1-3-5-10/h1-5,8-9,11-13,23-24H,6-7H2,(H,18,19,21,25)/t11-,12+,13+/m0/s |
| InChIKey | PIXHJAPVPCVZSV-YNEHKIRRSA-N |
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)CO)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Related products
2',3'-dideoxy-C(Ac)
Base-protected Nucleosides · CAS: 119818-52-9
BX-PN-00032',3'-dideoxy-C(Bz)
Base-protected Nucleosides · CAS: 120885-60-1
BX-PN-00052'-F-dG(DMF)
Base-protected Nucleosides · CAS: N/A
BX-PN-00062'-O-4'-C-Locked-5-Me-rC(Bz)
Base-protected Nucleosides · CAS: 206055-81-4
BX-PN-00072'-O-4'-C-Locked-rC(Bz)
Base-protected Nucleosides · CAS: 221229-74-9
BX-PN-00092'-O-4'-C-Locked-rG(iBu)
Base-protected Nucleosides · CAS: 206055-68-7
Frequently asked questions
Can the package size for 2'-dA(Bz) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0106 and CAS 4546-72-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Base-protected Nucleosides product family and its named chemistry.