2'-F Nucleosides
2'-Deoxy-2'-fluoro-5-iodouridine
Quick view. A dual-halogenated uridine derivative bearing iodine at the nucleobase 5-position and fluorine at the sugar 2'-position. CAS 55612-21-0. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2'-Deoxy-2'-fluoro-5-iodouridine is classified as 5-iodo 2'-fluoro uridine derivative (Formula C9H10FIN2O5; molecular weight 372.09 g/mol).
2'-Deoxy-2'-fluoro-5-iodouridine is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For 2'-Deoxy-2'-fluoro-5-iodouridine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 5-Iodo-2'-fluorouridine
- 2'-Fluoro-5-iodo-2'-deoxyuridine
Useful catalog search terms
- 55612-21-0
- MFCD00866922
Physicochemical data
| MDL number | MFCD00866922 |
|---|---|
| InChI | InChI=1S/C9H10FIN2O5/c10-5-6(15)4(2-14)18-8(5)13-1-3(11)7(16)12-9(13)17/h1,4-6,8,14-15H,2H2,(H,12,16,17)/t4-,5-,6-,8?/m1/s1 |
| InChIKey | IPVFGAYTKQKGBM-CDRSNLLMSA-N |
| SMILES | O=c1nc(O)c(I)cn1C1O[C@H](CO)[C@@H](O)[C@H]1F |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-Deoxy-2'-fluoro-5-iodouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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Frequently asked questions
Can the package size for 2'-Deoxy-2'-fluoro-5-iodouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FN-0179 and CAS 55612-21-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-F Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.