2'-F Nucleosides
2'-Deoxy-2'-fluoro-5-methylcytidine
Quick view. An unprotected 2'-deoxy-2'-fluoro-5-methylcytidine nucleoside, CAS 182495-80-3. CAS 182495-80-3. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2'-Deoxy-2'-fluoro-5-methylcytidine is classified as 2'-f nucleosides (Formula C10H14FN3O4; molecular weight 259.23).
2'-Deoxy-2'-fluoro-5-methylcytidine is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For 2'-Deoxy-2'-fluoro-5-methylcytidine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- Cytidine, 2'-deoxy-2'-fluoro-5-methyl-
Useful catalog search terms
- CAS 182495-80-3
- C10H14FN3O4
- QZZJZXAWLQYJFK-JXOAFFINSA-N
Physicochemical data
| Nucleobase | 5-Methylcytosine |
|---|---|
| Sugar modification | 2'-Deoxy-2'-fluoro |
| Protection state | Unprotected nucleoside |
| Stereochemistry | Assigned ribofuranosyl configuration |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-Deoxy-2'-fluoro-5-methylcytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-Deoxy-2'-fluoro-5-methylcytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FN-0057 and CAS 182495-80-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-F Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.