2'-F Nucleosides
2'-Fluoro-2,6-diaminopurine-2'-deoxyriboside
Quick view. A 2'-fluoro-2'-deoxyriboside bearing a 2,6-diaminopurine base, CAS 134444-47-6. CAS 134444-47-6. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2'-Fluoro-2,6-diaminopurine-2'-deoxyriboside is classified as 2'-f nucleosides (Formula C10H13FN6O3; molecular weight 284.25).
2'-Fluoro-2,6-diaminopurine-2'-deoxyriboside provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 2'-Fluoro-2,6-diaminopurine-2'-deoxyriboside, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 2-Amino-2'-deoxy-2'-fluoroadenosine
- 2-Amino-2'-fluoro-2'-deoxyadenosine
- (2R,3R,4R,5R)-5-(2,6-diamino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
Useful catalog search terms
- CAS 134444-47-6
- Wikidata Q82247674
- AstaTech ATE389310969
- MFCD00900994
Physicochemical data
| Systematic name | (2R,3R,4R,5R)-5-(2,6-diamino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol |
|---|---|
| InChI | InChI=1S/C10H13FN6O3/c11-4-6(19)3(1-18)20-9(4)17-2-14-5-7(12)15-10(13)16-8(5)17/h2-4,6,9,18-19H,1H2,(H4,12,13,15,16)/t3-,4-,6-,9-/m1/s1 |
| InChIKey | MHWHYOFBOWTAHZ-DXTOWSMRSA-N |
| SMILES | C1=NC2=C(N=C(N=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)F)N)N |
| Sugar substitution | Fluorine at 2' |
| Base substitution | Amino groups at purine C2 and C6 |
| Sugar class | 2'-Deoxyribofuranosyl nucleoside |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-Fluoro-2,6-diaminopurine-2'-deoxyriboside or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-MN-01812'-Fluoro-2'-deoxyuridine
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BX-MN-01822'-Deoxy-2'-fluorocytidine
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BX-MN-01832'-Deoxy-2'-fluoroguanosine
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Frequently asked questions
Can the package size for 2'-Fluoro-2,6-diaminopurine-2'-deoxyriboside be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FN-0234 and CAS 134444-47-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-F Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.