2'-O-MOE Nucleosides
2'-O-(2-Methoxyethyl)cytidine
Quick view. 2'-O-(2-Methoxyethyl)cytidine is a 2'-O-MOE-modified nucleoside building block for research-use modified-nucleoside and oligonucleotide chemistry. CAS 223777-16-0. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2'-O-(2-Methoxyethyl)cytidine is classified as 2'-o-moe nucleoside (Formula C12H19N3O6; molecular weight 301.30).
2'-O-(2-Methoxyethyl)cytidine — A 2'-O-(2-methoxyethyl)-modified cytidine building block for research-use modified-nucleoside and oligonucleotide chemistry.
For 2'-O-(2-Methoxyethyl)cytidine, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Confirmed or normalized name variants
- 2'-O-MOE-rC
- 2'-O-MOE Cytidine
- Cytidine, 2'-O-(2-methoxyethyl)-
Useful catalog search terms
- CAS 223777-16-0
Physicochemical data
| PubChem CID | 11077469 |
|---|---|
| InChIKey | YKOGMMXZKKVMBT-QCNRFFRDSA-N |
| Modification | 2-methoxyethyl ether at the ribose 2'-oxygen |
| InChI | InChI=1S/C12H19N3O6/c1-19-4-5-20-10-9(17)7(6-16)21-11(10)15-3-2-8(13)14-12(15)18/h2-3,7,9-11,16-17H,4-6H2,1H3,(H2,13,14,18)/t7-,9-,10-,11-/m1/s1 |
| SMILES | COCCO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)N)CO)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe 2'-O-(2-Methoxyethyl)cytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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2'-O-MOE Nucleosides · CAS: 545374-76-3
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2'-O-MOE Nucleosides · CAS: 244105-55-3
BX-MN-01682'-O-(2-Methoxyethyl)guanosine
2'-O-MOE Nucleosides · CAS: 473278-54-5
BX-MN-01692'-O-(2-Methoxyethyl)adenosine
2'-O-MOE Nucleosides · CAS: 168427-74-5
BX-MN-01712'-O-(2-Methoxyethyl)uridine
2'-O-MOE Nucleosides · CAS: 223777-15-9
BX-MN-01742'-O-(2-Methoxyethyl)-5-methyluridine
2'-O-MOE Nucleosides · CAS: 163759-49-7
Frequently asked questions
Can the package size for 2'-O-(2-Methoxyethyl)cytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0170 and CAS 223777-16-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-O-MOE Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.