2'-O-MOE Nucleosides
2'-O-(2-Methoxyethyl)inosine
Quick view. A 2'-O-(2-methoxyethyl) inosine nucleoside building block for nucleoside and oligonucleotide synthesis research. CAS 545374-76-3. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2'-O-(2-Methoxyethyl)inosine is classified as 2'-o-moe nucleosides (Formula C13H18N4O6; molecular weight 326.31).
2'-O-(2-Methoxyethyl)inosine — Modified inosine building block for nucleoside and oligonucleotide synthesis research.
For 2'-O-(2-Methoxyethyl)inosine, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Confirmed or normalized name variants
- 2'-O-MOE-rI
Useful catalog search terms
- CAS 545374-76-3
Physicochemical data
| InChIKey | YVCRYUJBJVEBAK-QYVSTXNMSA-N |
|---|---|
| Nucleoside identity | Inosine |
| Sugar modification | 2'-O-(2-methoxyethyl) |
| InChI | InChI=1S/C13H18N4O6/c1-21-2-3-22-10-9(19)7(4-18)23-13(10)17-6-16-8-11(17)14-5-15-12(8)20/h5-7,9-10,13,18-19H,2-4H2,1H3,(H,14,15,20)/t7-,9-,10-,13-/m1/s1 |
| SMILES | COCCO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=CNC3=O)CO)O |
| PubChem CID | 136161601 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe 2'-O-(2-Methoxyethyl)inosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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2'-O-MOE Nucleosides · CAS: 244105-55-3
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2'-O-MOE Nucleosides · CAS: 473278-54-5
BX-MN-01692'-O-(2-Methoxyethyl)adenosine
2'-O-MOE Nucleosides · CAS: 168427-74-5
BX-MN-01702'-O-(2-Methoxyethyl)cytidine
2'-O-MOE Nucleosides · CAS: 223777-16-0
BX-MN-01712'-O-(2-Methoxyethyl)uridine
2'-O-MOE Nucleosides · CAS: 223777-15-9
BX-MN-01742'-O-(2-Methoxyethyl)-5-methyluridine
2'-O-MOE Nucleosides · CAS: 163759-49-7
Frequently asked questions
Can the package size for 2'-O-(2-Methoxyethyl)inosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2OMN-0001 and CAS 545374-76-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-O-MOE Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.