2'-F Nucleosides
8-Chloro-2'-deoxy-2'-fluoroadenosine
Quick view. 8-Chloro-2'-deoxy-2'-fluoroadenosine is listed for research-use inquiry under 2'-F Nucleosides. Its identity is controlled by the retained exact structure and product-form evidence because no public CAS Registry Number is assigned. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
8-Chloro-2'-deoxy-2'-fluoroadenosine is classified as 2'-f nucleosides (Formula C10H11ClFN5O3; molecular weight 303.68 g/mol).
8-Chloro-2'-deoxy-2'-fluoroadenosine is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For 8-Chloro-2'-deoxy-2'-fluoroadenosine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Physicochemical data
| CAS status | No public CAS assigned |
|---|---|
| Identity control | Reviewed exact name, structure, and product form |
| InChIKey | RHTNRUHTRGZHIP-DXTOWSMRSA-N |
| InChI | InChI=1S/C10H11ClFN5O3/c11-10-16-5-7(13)14-2-15-8(5)17(10)9-4(12)6(19)3(1-18)20-9/h2-4,6,9,18-19H,1H2,(H2,13,14,15)/t3-,4-,6-,9-/m1/s1 |
| SMILES | C1=NC(=C2C(=N1)N(C(=N2)Cl)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)F)N |
| Canonical SMILES | C1=NC(=C2C(=N1)N(C(=N2)Cl)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)F)N |
| PubChem CID | 170902001 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 8-Chloro-2'-deoxy-2'-fluoroadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-MN-01812'-Fluoro-2'-deoxyuridine
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BX-MN-01822'-Deoxy-2'-fluorocytidine
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BX-MN-01832'-Deoxy-2'-fluoroguanosine
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BX-2FN-00034'-Azido-2'-deoxy-2'-fluoroaracytidine
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Frequently asked questions
Can the package size for 8-Chloro-2'-deoxy-2'-fluoroadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FN-0201, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-F Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.