Cap Analogs
m7(3'-OMeG)(5')ppp(5')(2'-OMeG)pG ammonium salt
Quick view. A modified GGG trinucleotide Cap1 analog in ammonium-salt form for RNA-synthesis research. CAS 2089461-54-9 and the listed composition refer to the free-acid identity; ammonium stoichiometry is variable. CAS 2089461-54-9. Catalog target purity: ≥98%. Availability: Inquiry only; contact BX Lab to confirm current availability.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
m7(3'-OMeG)(5')ppp(5')(2'-OMeG)pG ammonium salt is classified as cap analogs (Formula C33H45N15O25P4 (free acid); molecular weight 1175.69 (free acid)).
m7(3'-OMeG)(5')ppp(5')(2'-OMeG)pG ammonium salt — Modified trinucleotide Cap1 analog for RNA capping and modification research.
For m7(3'-OMeG)(5')ppp(5')(2'-OMeG)pG ammonium salt, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- CAP GGG(3'OMe) m7(3'OMeG)(5')ppp(5')(2'OMeG)pG Ammonium Salt
- m7(3'OMeG)ppp(2'OMeG)pG ammonium salt
- CAP GGG(3'OMe)
- BRP-00638
Useful catalog search terms
- CAS 2089461-54-9
- m7(3'OMeG)ppp(2'OMeG)pG
Physicochemical data
| Related CAS | 2089461-54-9 (free acid) |
|---|---|
| Counterion form | Ammonium salt (xNH4; stoichiometry unspecified) |
| Nucleotide shorthand | m7(3'-OMeG)(5')ppp(5')(2'-OMeG)pG |
| Cap classification | Cap1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
- 3′-O-methylation provides a defined blocked ribose terminus and is analytically distinguishable from the corresponding 2′-O-methyl isomer.
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
- The 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe m7(3'-OMeG)(5')ppp(5')(2'-OMeG)pG ammonium salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-CA-0003m7G(UNA)(5')ppp(5')(2'-OMeA)pG triammonium
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BX-CA-0004m7G(5')vppp(5')(2'-OMeA)pG triammonium
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BX-CA-0005CAP 6 m7G(LNA)(5')ppp(5')(2'OMeA)pG Triammonium Salt
Cap Analogs · CAS: N/A
BX-CA-0006CAP 7 m7G(HNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: N/A
Frequently asked questions
Can the package size for m7(3'-OMeG)(5')ppp(5')(2'-OMeG)pG ammonium salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-CA-0018 and CAS 2089461-54-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.