Cap Analogs
CAP m7(3'-OMeG)(5')vppp(5')(2'-OMe, m6A)pU Ammonium Salt
Quick view. A modified trinucleotide cap analog in triammonium form. Inner-salt and triammonium composition values are listed separately. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
CAP m7(3'-OMeG)(5')vppp(5')(2'-OMe, m6A)pU Ammonium Salt is classified as cap analogs.
CAP m7(3'-OMeG)(5')vppp(5')(2'-OMe, m6A)pU Ammonium Salt supports modified RNA/antisense designs where methylated ribose positions are used to improve stability or reduce unwanted immune stimulation.
For CAP m7(3'-OMeG)(5')vppp(5')(2'-OMe, m6A)pU Ammonium Salt, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- m7(3'-OMeG)vppp(2'-OMe,m6A)pU triammonium
- CAP1813
Useful catalog search terms
- CAP m7(3'-OMeG)(5')vppp(5')(2'-OMe, m6A)pU
- m7(3'-OMeG)vppp(2'-OMe,m6A)pU
Physicochemical data
| CAS | No public CAS assigned |
|---|---|
| Inner-salt formula | C34H46N12O24P4 |
| Inner-salt molecular weight | 1130.70 |
| Triammonium formula | C34H55N15O24P4 |
| Triammonium molecular weight | 1181.78 |
| Nucleotide shorthand | m7(3'-OMeG)(5')vppp(5')(2'-OMe,m6A)pU |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
- 3′-O-methylation provides a defined blocked ribose terminus and is analytically distinguishable from the corresponding 2′-O-methyl isomer.
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
- The 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe CAP m7(3'-OMeG)(5')vppp(5')(2'-OMe, m6A)pU Ammonium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
ARCA (m2(7,3'-O)GpppG)
Cap Analogs · CAS: 400806-46-4
BX-CA-0002A(5')ppp(5')(2'-OMeA)pG tetraammonium
Cap Analogs · CAS: N/A
BX-CA-0003m7G(UNA)(5')ppp(5')(2'-OMeA)pG triammonium
Cap Analogs · CAS: N/A
BX-CA-0004m7G(5')vppp(5')(2'-OMeA)pG triammonium
Cap Analogs · CAS: 3038327-80-6
BX-CA-0005CAP 6 m7G(LNA)(5')ppp(5')(2'OMeA)pG Triammonium Salt
Cap Analogs · CAS: N/A
BX-CA-0006CAP 7 m7G(HNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: N/A
Frequently asked questions
Can the package size for CAP m7(3'-OMeG)(5')vppp(5')(2'-OMe, m6A)pU Ammonium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-CA-0019, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Cap Analogs product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.