Cap Analogs
m7(3'-OMeG)(5')vppp(5')(2'-OMeA)pU ammonium salt
Quick view. A modified trinucleotide cap analog in ammonium form for in-vitro nucleotide and RNA-synthesis research. CAS 3056979-94-0 and the listed composition refer to the inner-salt identity. CAS 3056979-94-0. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
m7(3'-OMeG)(5')vppp(5')(2'-OMeA)pU ammonium salt is classified as cap analogs (Formula C33H44N12O24P4 (inner salt); molecular weight 1116.67 (inner salt)).
m7(3'-OMeG)(5')vppp(5')(2'-OMeA)pU ammonium salt — Modified nucleotide material for in-vitro nucleotide and RNA-synthesis research.
For m7(3'-OMeG)(5')vppp(5')(2'-OMeA)pU ammonium salt, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- CAP m7(3'-OMeG)(5')vppp(5')(2'-OMeA)pU Ammonium Salt
- m7(3'-OMeG)vppp(2'-OMeA)pU
- CAP1812
- TNU1838
Useful catalog search terms
- CAP m7(3'-OMeG)(5')vppp(5')(2'-OMeA)pU
- CAS 3056979-94-0
Physicochemical data
| Related CAS | 3056979-94-0 (inner salt) |
|---|---|
| Counterion form | Ammonium product; stoichiometry unspecified |
| Nucleotide shorthand | m7(3'-OMeG)(5')vppp(5')(2'-OMeA)pU |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
- 3′-O-methylation provides a defined blocked ribose terminus and is analytically distinguishable from the corresponding 2′-O-methyl isomer.
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
- The 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe m7(3'-OMeG)(5')vppp(5')(2'-OMeA)pU ammonium salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-CA-0003m7G(UNA)(5')ppp(5')(2'-OMeA)pG triammonium
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BX-CA-0004m7G(5')vppp(5')(2'-OMeA)pG triammonium
Cap Analogs · CAS: 3038327-80-6
BX-CA-0005CAP 6 m7G(LNA)(5')ppp(5')(2'OMeA)pG Triammonium Salt
Cap Analogs · CAS: N/A
BX-CA-0006CAP 7 m7G(HNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: N/A
Frequently asked questions
Can the package size for m7(3'-OMeG)(5')vppp(5')(2'-OMeA)pU ammonium salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-CA-0020 and CAS 3056979-94-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Cap Analogs product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.