Cap Analogs
m7G(5')ppp(5')(2'-OMeG) ammonium salt
Quick view. A dinucleotide Cap1 analogue in variable ammonium form for in-vitro RNA transcription and cap-analogue research. CAS 57718-00-0 and the listed composition refer to the free acid. CAS 57718-00-0. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
m7G(5')ppp(5')(2'-OMeG) ammonium salt is classified as cap analogs (Formula C22H31N10O18P3 (free acid); molecular weight 816.46 (free acid)).
m7G(5')ppp(5')(2'-OMeG) ammonium salt — Cap1-related in-vitro RNA transcription and cap-analogue research.
For m7G(5')ppp(5')(2'-OMeG) ammonium salt, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- CAP m7G(5')ppp(5')(2'OMeG) Ammonium Salt
- m7GpppGm ammonium salt
- M7-GpppG(2'OMe) ammonium salt
- BRP-00649
Useful catalog search terms
- CAS 57718-00-0
Physicochemical data
| Related CAS | 57718-00-0 (free acid) |
|---|---|
| Counterion form | Ammonium salt; stoichiometry variable |
| Nucleotide shorthand | m7G(5')ppp(5')(2'-OMeG) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe m7G(5')ppp(5')(2'-OMeG) ammonium salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
ARCA (m2(7,3'-O)GpppG)
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BX-CA-0002A(5')ppp(5')(2'-OMeA)pG tetraammonium
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BX-CA-0003m7G(UNA)(5')ppp(5')(2'-OMeA)pG triammonium
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BX-CA-0004m7G(5')vppp(5')(2'-OMeA)pG triammonium
Cap Analogs · CAS: 3038327-80-6
BX-CA-0005CAP 6 m7G(LNA)(5')ppp(5')(2'OMeA)pG Triammonium Salt
Cap Analogs · CAS: N/A
BX-CA-0006CAP 7 m7G(HNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: N/A
Frequently asked questions
Can the package size for m7G(5')ppp(5')(2'-OMeG) ammonium salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-CA-0022 and CAS 57718-00-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.