2'-O-MOE Nucleosides
5'-O-DMTr-2'-O-MOE-N4-acetylcytidine
Quick view. A protected modified cytidine bearing 5'-O-dimethoxytrityl, 2'-O-(2-methoxyethyl) and N4-acetyl groups, CAS 1345716-47-3. CAS 1345716-47-3. Catalog target purity: ≥98%. Availability: Inquiry only; contact BX Lab to confirm current availability.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
5'-O-DMTr-2'-O-MOE-N4-acetylcytidine is classified as 2'-o-moe nucleosides (Formula C35H39N3O9; molecular weight 645.71).
5'-O-DMTr-2'-O-MOE-N4-acetylcytidine — Protected modified cytidine building block for oligonucleotide synthesis.
For 5'-O-DMTr-2'-O-MOE-N4-acetylcytidine, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Confirmed or normalized name variants
- 5'-O-DMT-N4-Ac-2'-O-(2-methoxyethyl)cytidine
- 5'-O-DMTr-2'-O-MOE-Cytidine(N-Ac)
Useful catalog search terms
- CAS 1345716-47-3
- BOC Sciences BRP-00744
- ChemGenes India CGIDPM-1121
- RLHWWSNMWZITIE-WXQJYUTRSA-N
Physicochemical data
| Systematic name | N-(1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide |
|---|---|
| InChIKey | RLHWWSNMWZITIE-WXQJYUTRSA-N |
| Canonical SMILES | O=C1N=C(C=CN1C2OC(COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)C(O)C2OCCOC)NC(=O)C |
| 5'-hydroxyl protection | Dimethoxytrityl (DMTr) |
| 2'-substitution | O-(2-methoxyethyl) (MOE) |
| Nucleobase protection | N4-acetyl cytidine |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe 5'-O-DMTr-2'-O-MOE-N4-acetylcytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
2'-O-(2-Methoxyethyl)inosine
2'-O-MOE Nucleosides · CAS: 545374-76-3
BX-MN-01672'-O-(2-Methoxyethyl)-5-methylcytidine
2'-O-MOE Nucleosides · CAS: 244105-55-3
BX-MN-01682'-O-(2-Methoxyethyl)guanosine
2'-O-MOE Nucleosides · CAS: 473278-54-5
BX-MN-01692'-O-(2-Methoxyethyl)adenosine
2'-O-MOE Nucleosides · CAS: 168427-74-5
BX-MN-01702'-O-(2-Methoxyethyl)cytidine
2'-O-MOE Nucleosides · CAS: 223777-16-0
BX-MN-01712'-O-(2-Methoxyethyl)uridine
2'-O-MOE Nucleosides · CAS: 223777-15-9
Frequently asked questions
Can the package size for 5'-O-DMTr-2'-O-MOE-N4-acetylcytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2MOE-0003 and CAS 1345716-47-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-O-MOE Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.